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HRID751311

反应详情

EQUATION

反应方程式

HRID 751311 的结构方程式

REACTANTS

反应物

2
结构：CC(C)(C)OC(=O)n1ccc2c(Br)cccc21
HCID40425427

tert-Butyl 4-bromo-1H-indole-1-carboxylate

C13H14BrNO2

结构：OB(O)c1c(-c2ccccn2)nn2c1CCC2
HCID59710031

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)n1ccc2c(-c3c(-c4ccccn4)nn4c3CCC4)cccc21
HCID58611961

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

The titled intermediate was made via Preparation 33 (General Suzuki Coupling Method D) from 4-bromo-indole-1-carboxylic acid tert-butyl ester and 2-(pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-boronic acid (Preparation 5). MS (ESI) m/e 401 (M+1). TLC (SiO2): Rf0.5 (1:1 methylene chloride/[80:18:2 chloroform/methanol/concentrated aqueous ammonium hydroxide]).