HCID 67371284, compound → HCID 67371597, compound

Participants

Reaction Steps

The title compound is prepared following the procedures of WO, 00 55159 as follows. A mixture of (3-nitropyridin-4-yl)acetic acid benzyl ester (1.10 g, 5.23 mmol), 10% palladium on charcoal (200 mg) and denatured alcohol (100 mL) is stirred under an atmosphere of hydrogen for 6 hr. The catalyst is removed by filtration through a pad of Hi-Flo and the filtrate is concentrated to yield (3-aminopyridin-4-yl)acetic acid benzyl ester (0.92 g, 98% yield) as a yellow-brown oil. MS 181 (M+H).

Provenance & Evidence