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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 751416Generated: November 1, 2026

Hydrochloric Acid → HCID 11440932, compound

https://huagongshe.com/reaction/751416

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPiperazineHCID 4837—
ReactantHCID 86035950HCID 86035950—
ProductHCID 11440932HCID 1144093237%

Reaction Steps

N-[3-(2-chloro-3-formyl-indol-1-yl)phenyl]-acetamide is reacted with piperazine as described in Step 2 of Example 29 and subsequently treated with hydrochloric acid as described in Example 44 to afford N-{3-[3-Formyl-2-(piperazin-1-yl)-indol-1-yl]phenyl}-acetamide hydrochloride (37% yield) as a cream solid. ESI/MS 363 (M+H); RT 2.2 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07405300B2
Source datasetuspto-grants-2008_07
ORD IDord-560af813e2604dcfb6582c64f842f9fd
Source noteuspto-grants-2008_07