反应详情

温度

15 °C

Dissolve the brown oil in tetrahydrofuran (500 mL), add distilled water (100 mL), and cool the mixture to 15° C. Add 1M aqueous hydrochloric acid (100 mL), then stir at 15° C. for 2 hours. Add solid sodium hydrogen carbonate until the reaction mixture is basic, and saturate by adding solid sodium chloride. Separate, filter, and concentrate under reduced pressure to obtain 9.3 of a brown oil, which is a mixture of the title compound and 2-nitrophenethyl alcohol.

1. additionadd
2. distillationdistilled water (100 mL)
3. additionAdd 1M aqueous hydrochloric acid (100 mL)
4. additionAdd solid sodium hydrogen carbonate until the reaction mixture
5. concentrationsaturate
6. additionby adding solid sodium chloride
7. customSeparate
8. filtrationfilter
9. concentrationconcentrate under reduced pressure
10. customto obtain 9.3 of a brown oil, which