Ethyl vinyl ether → 4-Ethoxy-1,1,1-trifluoro-3-buten-2-one

HRID 751545Notes

Reaction equation

[CH:1]([O:3][CH2:4][CH3:5])=[CH2:2].[F:6][C:7]([F:12])([F:11])[C:8](Cl)=[O:9]>>[CH2:1]([O:3][CH:4]=[CH:5][C:8](=[O:9])[C:7]([F:12])([F:11])[F:6])[CH3:2]

Participants

Reactant 2

HCID 8023Ethyl vinyl ether

HCID 61106Trifluoroacetyl chloride

Product 1

HCID 27803954-Ethoxy-1,1,1-trifluoro-3-buten-2-one

Procedure

Reaction between ethyl vinyl ether and trifluoroacetyl chloride to form 4-ethoxy-1,1,1-trifluoro-3-buten-2-one (“ETFBO”) in the absence of an acid-capturing agent and in the presence of a stabilizer for the alkenone that is to be prepared.

Sources & evidence

ORD record: ord-12da014bb07f40019a9f03f00bb409cd
Source dataset: uspto-grants-2008_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07405328B2

Reaction notes

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