2-Aminomethyl-1,4-benzodioxane → HCID 11484695, compound

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Reaction Steps

The title compound was prepared as outlined in EXAMPLE 1 from 5-chloro-1H-pyrrolo[2,3-c]pyridine-2-carboxylic acid (Preparation 18) and 2,3-dihydrobenzo[1,4]dioxin-2-ylmethylamine. The product was purified by mass directed purification to give the title compound as a yellow solid. δH (CD3OD): 3.69–3.73 (2H, m), 3.97–4.03 (1H, m), 4.32–4.42 (2H, m), 6.77–6.88 (4H, m), 7.10 (1H, s), 7.67 (1H, s), 8.58 (1H, s); m/z (ES+)=344 [M+H]+.

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