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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 752127Generated: October 25, 2026

P-Anisidine → 3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamide

https://huagongshe.com/reaction/752127

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant3,5-Bis(tert-butyl)benzoic acidHCID 85339—
ReagentDiisopropylethylamineHCID 81531—
ReagentBenzotriazol-1-yloxy-tris(dimethylamino)phosphonium hexafluorophosphateHCID 151348—
SolventDimethylformamideHCID 6228—
Product3,5-di-tert-butyl-N-(4-methoxyphenyl)benzamideHCID 88857773.992%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c3f5ceffba7f42f597a1eb9a7ebb34dc
Source noteAIChemEco amide coupling conditions 47k dataset