反应详情

1-Pyridin-3-yl-butane-1,3-dione (step 1) (500 mg, 3.06 mmol) was dissolved in MeOH (20 ml). Hydrazine monohydrate (230 mg, 223 μl, 4.60 mmol) was added and the resulting mixture was stirred at RT for 1 hour. After cooling to RT, the solvent was removed in vacuo. The crude residue was dissolved in DCM, dried over (MgSO4) filtered and concentrated in vacuo to afford the title compound which was used without further purification.

1. temperatureAfter cooling to RT
2. customthe solvent was removed in vacuo
3. dissolutionThe crude residue was dissolved in DCM
4. dry with materialdried over (MgSO4)
5. filtrationfiltered
6. concentrationconcentrated in vacuo