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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 75681Generated: October 26, 2026

tert-butyl 5-(1-phenyl-1H-tetrazol-5-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate → HCID 66211639, compound

https://huagongshe.com/reaction/75681

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl 5-(1-phenyl-1H-tetrazol-5-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylateHCID 71285583—
SolventDichloromethaneHCID 6344—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 66211639HCID 66211639—

Reaction Steps

tert-butyl 5-(1-phenyl-1H-tetrazol-5-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (100 mg) was dissolved in 10% TFA solution in CH2Cl2 (10 mL). The reaction was stirred at room temperature for 24 hours. After removal of solvents, the residue, crude 2-(1-phenyl-1H-tetrazol-5-yl)octahydropyrrolo[3,4-c]pyrrole, was used in the further reactions without purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08835454B2
Source datasetuspto-grants-2014_09
ORD IDord-589d9939fbc34495af7154fbefb39b73
Source noteuspto-grants-2014_09