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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 75712Generated: October 29, 2026

Methylamine → 7-methoxy-N4-(2-morpholinophenyl)quinazolin-4,6-diamine

https://huagongshe.com/reaction/75712

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant7-methoxy-N-(2-morpholinophenyl)-6-nitroquinazolin-4-amineHCID 66608931—
Product7-methoxy-N4-(2-morpholinophenyl)quinazolin-4,6-diamineHCID 6660975335%

Reaction Steps

The procedure of Example 23 was repeated except for using 7-methoxy-N-(2-morpholinophenyl)-6-nitroquinazolin-4-amine instead of 7-methoxy-6-nitroquinazolin-4-yl)methylamine in <Step 7> to obtain the title compound (65 mg, 35%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08835458B2
Source datasetuspto-grants-2014_09
ORD IDord-1f1d8061b7934b6bbb47a3d0e1b661e6
Source noteuspto-grants-2014_09