HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Pyrrolidone → 1-(3-(Benzylthio)-2-methylphenyl)pyrrolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Pyrrolidone | HCID 12025 | — |
| Reactant | Benzyl(3-bromo-2-methylphenyl)sulfane | HCID 66911186 | — |
| Product | 1-(3-(Benzylthio)-2-methylphenyl)pyrrolidin-2-one | HCID 66911127 | — |
Reaction Steps
Intermediate 24 (14.08 g, 48 mmol) and pyrrolidin-2-one (4.9 g, 57.6 mmol) were converted to intermediate 25 as described in example 1; 1.5). The crude product (14.6 g) was used without purification in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08835653B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-e50f37a17a0c431eb0ab23a5be0457ad |
| Source note | uspto-grants-2014_09 |