反应详情

The filtrate obtained at dibenzoyl-d-tartrate salt stage (step.ii), was treated with a small amount of diisopropyl ether to remove any traces of dibenzoyl-d-tartaric acid and was concentrated under reduced pressure at 55° C. The residue obtained was stirred with small amount of acetone and filtered to obtain D-tert-leucine as a colorless solid (90% yield, 98.8% D-tert-leucine and 1.2% L-tert-leucine).

1. customto remove any traces of dibenzoyl-d-tartaric acid
2. concentrationwas concentrated under reduced pressure at 55° C
3. customThe residue obtained
4. filtrationfiltered