反应详情

温度

85 °C

Ammonium hydroxide (50 mL, 30%) solution was placed in an autoclave and D-tert-leucine (5 g) was added. Autoclave was closed and the contents were heated to 85° C. under stirring for 12 hours. After cooling the solution was transferred and concentrated under vacuum at 55° C. The solid residue obtained was stirred with acetone (20 mL), filtered and dried to obtain DL-tert-leucine (4.6 g, 92% yield, L-isomer: 42%, D-isomer: 58%)

1. additionwas added
2. customAutoclave was closed
3. temperatureAfter cooling the solution
4. concentrationconcentrated under vacuum at 55° C
5. customThe solid residue obtained
6. filtrationfiltered
7. customdried