反应详情

温度

85 °C

Method 7—Step b A mixture of N-(2-Amino-5-chloro-phenyl)-5-bromo-2-fluoro-benzamide (1.60 g, 4.67 mmol) in acetic acid (10 mL) was heated at 85° C. overnight. Solvent was removed under reduced pressure and the solid obtained was washed with dichloromethane and dried to obtain 1.40 g of the title compound (93%).

1. customSolvent was removed under reduced pressure
2. customthe solid obtained
3. washwas washed with dichloromethane
4. customdried