反应详情

5-Fluoro-2-nitrobenzoic acid (15.0 g, 81.0 mmol) was refluxed in thionyl chloride (67.5 g, 567 mmol) for 2.5 hours. The reaction mixture was allowed to cool to room temperature and the excess thionyl chloride removed under reduced pressure, to afford 5-fluoro-2-nitrobenzoyl chloride (16.5 g, 81.0 mmol).

1. customthe excess thionyl chloride removed under reduced pressure