反应详情

According to method G, (S)-6-bromo-1,2,3,4-tetrahydronaphthalen-2-ylamine was coupled with 5-hydroxypyridine-2-carboxylic acid and the product was then alkylated on the phenolic hydroxyl function with bromomethylcyclopropane according to method a Finally, the amide function was alkylated according to method B with methyl iodide. The product was thus obtained with the molecular weight of 415.33 (C21H23BrN2O2); MS (ESI): 415 (M+H+).

1. customThe product was thus obtained with the molecular weight of 415.33 (C21H23BrN2O2)