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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 77424Generated: October 28, 2026

Pyrrolidine → [(S)-6-(pyrrolidine-1-carbonyl)-1,2,3,4-tetrahydronaphthalen-2-yl]carbamic acid tert-butyl ester

https://huagongshe.com/reaction/77424

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant(S)-6-tert-butoxycarbonylamino-5,6,7,8-tetrahydronaphthalene-2-carboxylic acidHCID 66663497—
Product[(S)-6-(pyrrolidine-1-carbonyl)-1,2,3,4-tetrahydronaphthalen-2-yl]carbamic acid tert-butyl esterHCID 66663930—

Reaction Steps

According to method G, (S)-6-tert-butoxycarbonylamino-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid was reacted with pyrrolidine. The product was thus obtained with the molecular weight of 344.46 (C20H28N2O3); MS (ESI): 345 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841290B2
Source datasetuspto-grants-2014_09
ORD IDord-20508aeff6de43bba9250bbf1c139661
Source noteuspto-grants-2014_09