huagongshe.com
HRID77433

反应详情

EQUATION

反应方程式

HRID 77433 的结构方程式

REACTANTS

反应物

1
结构：CCOC(=O)C(=Cc1ccc(Br)s1)N=[N+]=[N-]
HCID73166977

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1cc2sc(Br)cc2[nH]1
HCID13164349

Ethyl 2-bromo-4H-thieno[3,2-b]pyrrole-5-carboxylate

C9H8BrNO2S

收率 82%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Cc1ccccc1C
溶剂HCID7237

o-Xylene

C8H10

PROCEDURE

实验过程

Acrylate 60 (3.81 g, 12.6 mmol) in o-xylene was refluxed for 20 min. After removing the o-xylene, the crude product was purified by column chromatography (EtOAc/Hexane: 1/10) to give carboxylate 61 (2.83 g, 82%) as a white solid.

WORKUP

后处理

  1. customAfter removing the o-xylene
  2. customthe crude product was purified by column chromatography (EtOAc/Hexane: 1/10)