HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 178520194, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | Dimethylaminopropyl carbodiimide hydrochloride | HCID 21899179 | — |
| Reactant | 4-Chlorobenzyl piperazine-1-carboxylate hydrochloride | HCID 66664396 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 178520194 | HCID 178520194 | — |
Reaction Steps
7.3 220 mg (1.24 mmol) of 23, 362 mg (1.24 mmol) of 4-chlorobenzyl piperazine-1-carboxylate hydrochloride, 168 mg (1.24 mmol) of 1-hydroxybenzotriazole (HOBt), 143 mg (1.24 mmol) of N-methylmorpholine and 238 mg (1.24 mmol) of 3-dimethylaminopropylcarbodiimide hydrochloride (DAPECI) are stirred at RT for 48 h in 10 ml of DMF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08841324B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-9c0c5010c8dc468cac1b68cd317e6b5d |
| Source note | uspto-grants-2014_09 |