Allyl bromide → 3-allyl-5-methylthiazol-2(3H)-imine hydrobromide

HRID 78489Notes

Reaction equation

[NH2:1][C:2]1[S:3][C:4]([CH3:7])=[CH:5][N:6]=1.[CH2:8]([Br:11])[CH:9]=[CH2:10]>>[BrH:11].[CH2:10]([N:6]1[CH:5]=[C:4]([CH3:7])[S:3][C:2]1=[NH:1])[CH:9]=[CH2:8]

Participants

Reactant 2

HCID 7841Allyl bromide

HCID 3517702-Amino-5-methylthiazole

Product 1

HCID 686217733-allyl-5-methylthiazol-2(3H)-imine hydrobromide

Procedure

A mixture of 2-amino-5-methylthiazole (2.5 g) and allylbromide (3.31 g) was processed according to the method of Example 227A to afford the title compound that was taken directly to the next step. MS (ESI+) m/z 155 (M+H)+.

Sources & evidence

ORD record: ord-521a09c6f163469d9f86f28c990d4697
Source dataset: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08841334B2

Reaction notes

Loading…