Hexafluoroacetone trihydrate → HCID 11357953, compound
Reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([NH2:7])[S:5][CH:6]=1.O.O.O.[F:11][C:12]([F:20])([F:19])[C:13]([C:15]([F:18])([F:17])[F:16])=[O:14]>>[NH2:7][C:4]1[S:5][C:6]([C:13]([OH:14])([C:15]([F:18])([F:17])[F:16])[C:12]([F:20])([F:19])[F:11])=[C:2]([CH3:1])[N:3]=1Participants
3
Procedure
The title compound was prepared from commercially available of 4-methylthiazol-2-amine (Aldrich) and hexafluoroacetone trihydrate (Aldrich) using the procedure described in European Journal of Organic Chemistry, (21), 4286-4291; 2003. MS (ESI+) m/z 281 (M+H)+.
Sources & evidence
- ORD record
- ord-4e9ba0fcdf1c410fa7d97c2d7f3256d0
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08841334B2
Reaction notes
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