HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78595Generated: October 26, 2026
Triethylamine → HCID 178513395, compound
https://huagongshe.com/reaction/78595
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 3-Amino-6-bromopyrazine-2-carbonitrile | HCID 11052611 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178513395 | HCID 178513395 | 77% |
Reaction Steps
A mixture of 3-amino-6-bromo-pyrazine-2-carbonitrile (1 g, 5.025 mmol) was dissolved in MeOH (20.00 mL) and cooled to 0° C. Hydroxylamine hydrochloride (349.2 mg, 5.025 mmol) and triethylamine (508.5 mg, 700.4 μL, 5.025 mmol) were added and the reaction allowed to warm to ambient temperature. After 2 hours the resultant precipitate was filtered off and dried (898 mg, 77% Yield). MS (ES+) 234.89
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08841308B2 |
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| Source dataset | uspto-grants-2014_09 |
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| ORD ID | ord-cd496f633cdf4627964591ce8f645cbb |
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| Source note | uspto-grants-2014_09 |
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