反应详情

温度

30 °C

(3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl acetate (14.0 g) was dissolved in Methanol (42 ml). Potassium carbonate (0.34 g) was added to the reaction mass. Reaction mass was stirred at 25-35° C. till the completion of reaction. Reaction mass was concentrated to residue under vacuum at 40-45° C. Dichloromethane (42 ml) was charged to residue along with activated carbon (0.7 g) and stirred for 1 hr and then filtered through hyflow bed. Filtrate was concentrated to residue to get (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-ol (Yield 10.5 g)

1. customReaction mass
2. customReaction mass
3. concentrationwas concentrated to residue under vacuum at 40-45° C
4. additionDichloromethane (42 ml) was charged to residue along with activated carbon (0.7 g)
5. stirringstirred for 1 hr
6. filtrationfiltered through hyflow bed
7. concentrationFiltrate was concentrated to residue