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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7940Generated: October 28, 2026

4-carboxy-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-one → 4-hydroxymethyl-2-isobutyl-6-(4-methyl-phenyl)-2H-pyridazin-3-one

https://huagongshe.com/reaction/7940

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-carboxy-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-oneHCID 21991635—
ReactantHCID 178419042HCID 178419042—
Product4-hydroxymethyl-2-isobutyl-6-(4-methyl-phenyl)-2H-pyridazin-3-oneHCID 21991644—

Reaction Steps

Following the procedure of Example 1 (8), 4-carboxy-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-one was reacted to yield the title compound as slightly yellow needles (yield: 46.0%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-c276e1f8025c489e94c3d89be8644b2f
Source noteuspto-grants-2006_08