HRID7942

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID75994

1-Benzylpiperazine

C11H16N2

结构：Cc1ccc(-c2cc(COS(C)(=O)=O)c(=O)n(CC(C)C)n2)cc1

HCID21991589

未命名化合物

结构：Cc1ccc(-c2nn(CC(C)C)c(=O)c(N3CCN(C(=O)OC(C)(C)C)CC3)c2C)cc1F

HCID67214099

未命名化合物

PRODUCTS

生成物

结构：Cc1ccc(-c2cc(CN3CCN(Cc4ccccc4)CC3)c(=O)n(CC(C)C)n2)cc1

HCID21991487

未命名化合物

收率 97.7%

PROCEDURE

实验过程

Following the procedure of Example 1 (10), 2-isobutyl-4-methanesulfonyloxymethyl-6-(4-methylphenyl)-2H-pyridazin-3-one and 1-benzylpiperazine were reacted to yield the title compound as a pale yellow oil (yield: 97.7%).

WORKUP

后处理

customwere reacted

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-50745821803a42088dfeb550ab166f5e
来源数据集: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07087606B2
来源说明: uspto-grants-2006_08

反应 SMILES

C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2C(=O)N(CC(C)C)N=[C:18]([C:21]3[CH:26]=[CH:25][C:24](C)=C(F)C=3)[C:19]=2C)[CH2:10][CH2:9]1)=O)(C)(C)C.[CH2:34]([N:38]1[C:43](=[O:44])[C:42]([CH2:45]OS(C)(=O)=O)=[CH:41][C:40]([C:51]2[CH:56]=[CH:55][C:54]([CH3:57])=[CH:53][CH:52]=2)=[N:39]1)[CH:35]([CH3:37])[CH3:36].C(N1CCNCC1)C1C=CC=CC=1>>[CH2:14]([N:11]1[CH2:10][CH2:9][N:8]([CH2:45][C:42]2[C:43](=[O:44])[N:38]([CH2:34][CH:35]([CH3:37])[CH3:36])[N:39]=[C:40]([C:51]3[CH:56]=[CH:55][C:54]([CH3:57])=[CH:53][CH:52]=3)[CH:41]=2)[CH2:13][CH2:12]1)[C:19]1[CH:18]=[CH:21][CH:26]=[CH:25][CH:24]=1