HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Benzylpiperazine → 4-(4-benzyl-1-piperazinyl)methyl-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Benzylpiperazine | HCID 75994 | — |
| Edukt | 2-isobutyl-4-methanesulfonyloxymethyl-6-(4-methylphenyl)-2H-pyridazin-3-one | HCID 21991589 | — |
| Edukt | 4-(4-tert-butoxycarbonyl-1-piperazinyl)-methyl-6-(3-fluoro-4-methylphenyl)-2-isobutyl-2H-pyridazin-3-one | HCID 67214099 | — |
| Produkt | 4-(4-benzyl-1-piperazinyl)methyl-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-one | HCID 21991487 | 97,7% |
Reaktionsschritte
Following the procedure of Example 1 (10), 2-isobutyl-4-methanesulfonyloxymethyl-6-(4-methylphenyl)-2H-pyridazin-3-one and 1-benzylpiperazine were reacted to yield the title compound as a pale yellow oil (yield: 97.7%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07087606B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-50745821803a42088dfeb550ab166f5e |
| Quellennotiz | uspto-grants-2006_08 |