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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7947Generated: October 28, 2026

4-carboxy-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one → 4-methoxycarbonyl-6-(4-trifluoromethyl-phenyl)-2H-pyridazin-3-one

https://huagongshe.com/reaction/7947

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-carboxy-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-oneHCID 21991427—
Reactant4-(4-benzyl-1-piperazinyl)methyl-2-isobutyl-6-(4-methylphenyl)-2H-pyridazin-3-oneHCID 21991487—
Product4-methoxycarbonyl-6-(4-trifluoromethyl-phenyl)-2H-pyridazin-3-oneHCID 21991607—

Reaction Steps

Following the procedure of Example 1 (5), 4-carboxy-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one was reacted to yield the title compound as slightly yellow crystalline powder (yield: 88.5%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-b6623aafc3be420190abc80d4c625a60
Source noteuspto-grants-2006_08