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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7948Generated: October 27, 2026

4-carboxy-2-isobutyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one → 4-hydroxymethyl-2-isobutyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one

https://huagongshe.com/reaction/7948

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-carboxy-2-isobutyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-oneHCID 21991455—
ReactantHCID 178419042HCID 178419042—
Product4-hydroxymethyl-2-isobutyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-oneHCID 6721362528.1%

Reaction Steps

Following the procedure of Example 1 (8), 4-carboxy-2-isobutyl-6-(4-trifluoromethylphenyl)-2H-pyridazin-3-one was reacted to yield the title compound as colorless fine-needles (yield: 28.1%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-38f54bda284b4a1c97d183b361a15695
Source noteuspto-grants-2006_08