HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-(4-Fluoro-3-methylphenyl)-2-isobutyl-4-methane-sulfonyloxymethyl-2H-pyridazin-3-one → 4-carboxy-6-(3,4-difluorophenyl)-2-isobutyl-2H-pyridazin-3-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-(4-Fluoro-3-methylphenyl)-2-isobutyl-4-methane-sulfonyloxymethyl-2H-pyridazin-3-one | HCID 21991457 | — |
| Edukt | 6-(3,4-difluorophenyl)-2-isobutyl-4-methoxycarbonyl-2H-pyridazin-3-one | HCID 21991659 | — |
| Produkt | 4-carboxy-6-(3,4-difluorophenyl)-2-isobutyl-2H-pyridazin-3-one | HCID 21991638 | 91,4% |
Reaktionsschritte
Following the procedure of Example 1 (7), 6-(3,4-difluorophenyl)-2-isobutyl-4-methoxycarbonyl-2H-pyridazin-3-one was reacted to yield the title compound as colorless fine needles (yield: 91.4%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07087606B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-714bb13112614b41842047c2a94caf55 |
| Quellennotiz | uspto-grants-2006_08 |