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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7976Generated: October 28, 2026

Benzyl Chloride → 2-benzyl-6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one

https://huagongshe.com/reaction/7976

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl ChlorideHCID 7503—
Reactant6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-oneHCID 21991459—
Reactant6-(2,4-difluorophenyl)-4-hydroxymethyl-2-isobutyl-2H-pyridazin-3-oneHCID 21991662—
Product2-benzyl-6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-oneHCID 2199171471%

Reaction Steps

Following the procedure of Example 1 (6), 6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and benzyl chloride were reacted to yield the title compound as yellow needles (yield: 71.0%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-c691731ee11f4e87b3c2983c4e59d2bb
Source noteuspto-grants-2006_08