Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7977Generated: October 25, 2026

6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one → 2-benzyl-4-carboxy-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-one

https://huagongshe.com/reaction/7977

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-oneHCID 21991416—
Reactant2-benzyl-6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-oneHCID 21991714—
Product2-benzyl-4-carboxy-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-oneHCID 2199156565.2%

Reaction Steps

Following the procedure of Example 1 (7), 2-benzyl-6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one was reacted to yield the title compound as a pale yellow crystalline powder (yield: 65.2%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-e4cb384438354d1495d3e3a819bb7dae
Source noteuspto-grants-2006_08