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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7982Generated: October 25, 2026

6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one → 4-carboxy-2-cinnamyl-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-one

https://huagongshe.com/reaction/7982

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-oneHCID 21991416—
Reactant2-cinnamyl-6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-oneHCID 67213452—
Product4-carboxy-2-cinnamyl-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-oneHCID 6721335385.1%

Reaction Steps

Following the procedure of Example 1 (7), 2-cinnamyl-6-(4-fluoro-3-methylphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one was reacted to yield the title compound as pale yellow needles (yield: 85.1%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-fcf274a54078452a9ad50b4702e61f52
Source noteuspto-grants-2006_08