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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7990Generated: October 29, 2026

2-Cyclopropylmethyl-4-methoxycarbonyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one → 4-carboxy-2-cyclopropylmethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-one

https://huagongshe.com/reaction/7990

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Cyclopropylmethyl-4-methoxycarbonyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-oneHCID 12971771—
Reactant6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-oneHCID 21991416—
Product4-carboxy-2-cyclopropylmethyl-6-[4-(methylthio)phenyl]-2H-pyridazin-3-oneHCID 2199142498.2%

Reaction Steps

Following the procedure of Example 1 (7), 2-cyclopropylmethyl-4-methoxycarbonyl-6-[4-(methylthio)-phenyl]-2H-pyridazin-3-one was reacted to yield the title compound as a yellow crystalline powder (yield: 98.2%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-abb0a210dd504a5dadf137cc2aaedd23
Source noteuspto-grants-2006_08