Tetrahydrofuran → 3-amino-N-(3,4-dichlorophenyl)-2-piperid-1-yl-5-trifluoromethylbenzamide
Reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[Cl:1][c:2]1[cH:3][c:4]([NH:9][C:10]([c:11]2[c:12]([N:24]3[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]3)[c:13]([N+:21]([O-:22])=[O:23])[cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)=[O:30])[cH:5][cH:6][c:7]1[Cl:8].[H:31][H:32]>>[Cl:1][c:2]1[cH:3][c:4]([NH:9][C:10]([c:11]2[c:12]([N:24]3[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]3)[c:13]([NH2:21])[cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)=[O:30])[cH:5][cH:6][c:7]1[Cl:8]Participants
4
Sources & evidence
- ORD record
- ord-17d043a0a28445ddbc97e31749d0606e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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