Phosphorus oxychloride → 4-Chloro-2,6-bis(trifluoromethyl)quinoline

HRID 799491Notes

Reaction equation

HRID 799491 reaction equation
[OH:1][c:2]1[cH:3][c:4]([C:16]([F:17])([F:18])[F:19])[n:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]12.[P:20]([Cl:21])([Cl:22])([Cl:23])=[O:24]>>[c:2]1([Cl:22])[cH:3][c:4]([C:16]([F:17])([F:18])[F:19])[n:5][c:6]2[cH:7][cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[cH:10][c:11]12

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 1785161332,6-Bis(trifluoromethyl)quinolin-4(1H)-one

Product 1

HCID 6270374-Chloro-2,6-bis(trifluoromethyl)quinoline

Sources & evidence

ORD record
ord-c8eebd9cfe74442ba782785bbb9e3687
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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