Methanol → HCID 59615408, compound

HRID 799656Notes

Reaction equation

HRID 799656 reaction equation
[CH3:33][OH:34].[Cl:1][c:2]1[n:3][c:4]([C:9](=[O:10])[NH:11][c:12]2[cH:13][c:14]3[c:18]([cH:19][cH:20]2)[CH2:17][N:16]([c:21]2[s:22][c:23]([C:26](=[O:27])[O:28][CH2:29][CH3:30])[cH:24][n:25]2)[CH2:15]3)[nH:5][c:6]1[CH2:7][CH3:8].[Cl:35][CH2:36][Cl:37].[Li+:31].[OH-:32]>>[Cl:1][c:2]1[n:3][c:4]([C:9](=[O:10])[NH:11][c:12]2[cH:13][c:14]3[c:18]([cH:19][cH:20]2)[CH2:17][N:16]([c:21]2[s:22][c:23]([C:26](=[O:27])[OH:28])[cH:24][n:25]2)[CH2:15]3)[nH:5][c:6]1[CH2:7][CH3:8]

Participants

6

Reactant 5

HCID 887MethanolHCID 961HydroxideHCID 6344DichloromethaneHCID 28486Lithium ionHCID 67548627ethyl 2-(5-{[(4-chloro-5-ethyl-1H-imidazol-2-yl)carbonyl]amino}-1,3-dihydro-2H-isoindol-2-yl)-1,3-thiazole-5-carboxylate

Product 1

HCID 59615408HCID 59615408, compound

Sources & evidence

ORD record
ord-0a9003fa27aa4e978006e3daac5e91e9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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