Diethyl Ether → 1-t-Butylcarbamoyl-3-hydroxypyrrolidine

HRID 799661Notes

Reaction equation

HRID 799661 reaction equation
[C:17]([CH3:18])([CH3:19])([CH3:20])[N:21]=[C:22]=[O:23].[CH3:10][CH2:11][N:12]([CH2:13][CH3:14])[CH2:15][CH3:16].[CH3:24][CH2:25][O:26][CH2:27][CH3:28].[Cl:1][CH2:2][Cl:3].[OH:4][CH:5]1[CH2:6][NH:7][CH2:8][CH2:9]1>>[OH:4][CH:5]1[CH2:6][N:7]([C:22]([NH:21][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:23])[CH2:8][CH2:9]1

Participants

6

Reactant 5

HCID 3283Diethyl EtherHCID 6344DichloromethaneHCID 8471TriethylamineHCID 62412tert-Butyl isocyanateHCID 982104-Hydroxypyrrolidine

Product 1

HCID 196002891-t-Butylcarbamoyl-3-hydroxypyrrolidine

Sources & evidence

ORD record
ord-1fe336e24c0b49a2bf8e72bfbd4ced4d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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