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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 799737Generated: October 30, 2026

Acetone → 1'-(2,2,2-Trifluoroethyl)-spiro[indoline-3,4'-piperidin]-2-one

https://huagongshe.com/reaction/799737

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetoneHCID 180—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylamineHCID 8471—
Reactant2,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 80366—
ReactantSpiro(indole-3,4'-piperidin)-2(1H)-oneHCID 18435788—
Product1'-(2,2,2-Trifluoroethyl)-spiro[indoline-3,4'-piperidin]-2-oneHCID 18449358—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-dbb80c38d9ab461ab86391abde64e823
Source noteTest data from https://doi.org/10.1039/C8SC04228D