Trifluoroacetic acid → N-Desmethylflumazenil

HRID 799908Notes

Reaction equation

HRID 799908 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([O:27][CH3:28])[cH:29][cH:30][c:31]1[CH2:32][N:6]1[CH2:7][c:8]2[n:9]([cH:19][n:20][c:21]2[C:22](=[O:23])[O:24][CH2:25][CH3:26])-[c:10]2[c:11]([cH:14][c:15]([F:18])[cH:16][cH:17]2)[C:12]1=[O:13].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[NH:6]1[CH2:7][c:8]2[n:9]([cH:19][n:20][c:21]2[C:22](=[O:23])[O:24][CH2:25][CH3:26])-[c:10]2[c:11]([cH:14][c:15]([F:18])[cH:16][cH:17]2)[C:12]1=[O:13]

Participants

3

Reactant 2

HCID 6422Trifluoroacetic acidHCID 20515335ethyl 5-(2,4-dimethoxybenzyl)-8-fluoro-5,6-dihydro-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate

Product 1

HCID 6426758N-Desmethylflumazenil

Sources & evidence

ORD record
ord-ec5a7aa520f343e3a7d58d4fc3da03a9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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