Hydrochloric Acid → 3-(4-Cyclopropylmethoxy-phenoxy)-azetidine

HRID 799995Notes

Reaction equation

HRID 799995 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH:10]([O:12][c:13]2[cH:14][cH:15][c:16]([O:19][CH2:20][CH:21]3[CH2:22][CH2:23]3)[cH:17][cH:18]2)[CH2:11]1)([CH3:5])([CH3:6])[CH3:7].[CH2:27]1[O:28][CH2:29][CH2:30][O:31][CH2:32]1.[ClH:24].[Na+:26].[OH-:25]>>[NH:8]1[CH2:9][CH:10]([O:12][c:13]2[cH:14][cH:15][c:16]([O:19][CH2:20][CH:21]3[CH2:22][CH2:23]3)[cH:17][cH:18]2)[CH2:11]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 312751,4-DioxaneHCID 866890083-(4-Cyclopropylmethoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 866890093-(4-Cyclopropylmethoxy-phenoxy)-azetidine

Sources & evidence

ORD record
ord-dc3f038a3b1048ad9d5fd8a6d8204d87
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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