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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 800090Generated: October 26, 2026

Bicarbonate Ion → tert-Butyl 4-((3-bromo-5-(trifluoromethyl)benzyloxy)methyl)-4-(2,4-difluorophenyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/800090

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTetrahydrofuranHCID 8028—
Reactant2-Methylpropan-2-olateHCID 4574913—
Reactant3-Bromo-5-(trifluoromethyl)benzyl bromideHCID 22324272—
ReactantTert-butyl 4-(2,4-difluorophenyl)-4-(hydroxymethyl)piperidine-1-carboxylateHCID 58993620—
Producttert-Butyl 4-((3-bromo-5-(trifluoromethyl)benzyloxy)methyl)-4-(2,4-difluorophenyl)piperidine-1-carboxylateHCID 58993590—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTest data from https://doi.org/10.1039/C8SC04228D
ORD IDord-482f451002c242fa86f7c002c5bb3bdb
Source noteTest data from https://doi.org/10.1039/C8SC04228D