Bicarbonate Ion → tert-Butyl 4-((3-bromo-5-(trifluoromethyl)benzyloxy)methyl)-4-(2,4-difluorophenyl)piperidine-1-carboxylate

HRID 800090Notes

Reaction equation

[Br:24][c:25]1[cH:26][c:27]([CH2:35][Br:36])[cH:28][c:29]([C:31]([F:32])([F:33])[F:34])[cH:30]1.[C:55](=[O:56])([OH:57])[O-:58].[CH3:37][C:38]([CH3:39])([O-:40])[CH3:41].[F:1][c:2]1[c:3]([C:9]2([CH2:22][OH:23])[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1.[F:43][C:44]([F:45])([F:46])[C:47]([OH:48])=[O:49].[Na+:42].[Na+:59].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1>>[F:1][c:2]1[c:3]([C:9]2([CH2:22][O:23][CH2:35][c:27]3[cH:26][c:25]([Br:24])[cH:30][c:29]([C:31]([F:32])([F:33])[F:34])[cH:28]3)[CH2:10][CH2:11][N:12]([C:15](=[O:16])[O:17][C:18]([CH3:19])([CH3:20])[CH3:21])[CH2:13][CH2:14]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1