Hydroxide → 2,6-Difluoro-N-(2-(methyloxy)-5-{3-[2-(1,2,3,4-tetrahydro-7-isoquinolinylamino)-4-pyrimidinyl]pyrazolo[1,5-a]pyridin-2-yl}phenyl)benzamide

HRID 800143Notes

Reaction equation

[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[c:8]([O:45][CH3:46])[cH:9][cH:10][c:11](-[c:13]3[n:14][n:15]4[c:16]([cH:17][cH:18][cH:19][cH:20]4)[c:21]3-[c:22]3[n:23][c:24]([NH:28][c:29]4[cH:30][cH:31][c:32]5[c:37]([cH:38]4)[CH2:36][N:35]([C:39](=[O:40])[C:41]([F:42])([F:43])[F:44])[CH2:34][CH2:33]5)[n:25][cH:26][cH:27]3)[cH:12]2)[c:47]([F:51])[cH:48][cH:49][cH:50]1.[Li+:53].[OH-:52].[OH2:54]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[c:8]([O:45][CH3:46])[cH:9][cH:10][c:11](-[c:13]3[n:14][n:15]4[c:16]([cH:17][cH:18][cH:19][cH:20]4)[c:21]3-[c:22]3[n:23][c:24]([NH:28][c:29]4[cH:30][cH:31][c:32]5[c:37]([cH:38]4)[CH2:36][NH:35][CH2:34][CH2:33]5)[n:25][cH:26][cH:27]3)[cH:12]2)[c:47]([F:51])[cH:48][cH:49][cH:50]1