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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80016Generated: October 29, 2026

Chloroacetyl chloride → HCID 178463656, compound

https://huagongshe.com/reaction/80016

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloroacetyl chlorideHCID 6577—
ReactantO-ToluidineHCID 7242—
ReactantEthyl isothiocyanateHCID 10966—
ProductHCID 178463656HCID 178463656—

Reaction Steps

2-[(Z)-Ethylimino]-3-(2-methylphenyl)-thiazolidin-4-one is prepared following Method B and starting from o-tolylamine, chloroacetyl chloride and ethylisothiocyanate. LC-MS: tR=0.59 min, [M+1]+=235, 1H NMR (CDCl3): δ 7.36-7.28 (m, 3H), 7.15-7.10 (m, 1H), 4.01 (s, 2H), 3.41-3.30 (m, 2H), 2.19 (s, 3H), 1.20-1.13 (m, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE045174E1
Source datasetuspto-grants-2014_09
ORD IDord-a7da7dce8e724ea68d2843e50aca0c8e
Source noteuspto-grants-2014_09