2-Chlorobenzoic Acid → 2-Chloro-N-ethyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamide

HRID 800188Notes

Reaction equation

HRID 800188 reaction equation
[CH2:11]([CH3:12])[NH:13][CH2:14][C:15]([C:16]([F:17])([F:18])[F:19])([OH:20])[CH2:21][NH:22][c:23]1[c:24]2[cH:25][n:26][n:27](-[c:32]3[cH:33][cH:34][c:35]([F:38])[cH:36][cH:37]3)[c:28]2[cH:29][cH:30][cH:31]1.[OH:1][C:2](=[O:3])[c:4]1[cH:5][cH:6][cH:7][cH:8][c:9]1[Cl:10]>>[C:2](=[O:3])([c:4]1[cH:5][cH:6][cH:7][cH:8][c:9]1[Cl:10])[N:13]([CH2:11][CH3:12])[CH2:14][C:15]([C:16]([F:17])([F:18])[F:19])([OH:20])[CH2:21][NH:22][c:23]1[c:24]2[cH:25][n:26][n:27](-[c:32]3[cH:33][cH:34][c:35]([F:38])[cH:36][cH:37]3)[c:28]2[cH:29][cH:30][cH:31]1

Participants

3

Reactant 2

HCID 83742-Chlorobenzoic AcidHCID 593241253-(Ethylamino)-1,1,1-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-propanol

Product 1

HCID 452693542-Chloro-N-ethyl-N-[3,3,3-trifluoro-2-({[1-(4-fluorophenyl)-1H-indazol-4-yl]amino}methyl)-2-hydroxypropyl]benzamide

Sources & evidence

ORD record
ord-fecbc48141dc4e9f97460efb781e2754
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…