Tetrahydrofuran → N-[2-(6-Bromo-2H-pyrazolo[4,3-b]pyridin-2-yl)-1-cyano-1-methylethyl]-4-hexylbenzamide
Reaction equation
[CH2:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])[c:7]1[cH:8][cH:9][c:10]([C:11](=[O:12])[Cl:13])[cH:14][cH:15]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[NH2:16][C:17]([C:18]#[N:19])([CH2:20][n:21]1[n:22][c:23]2[c:24]([n:25][cH:26][c:27]([Br:29])[cH:28]2)[cH:30]1)[CH3:31]>>[CH2:1]([CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])[c:7]1[cH:8][cH:9][c:10]([C:11](=[O:12])[NH:16][C:17]([C:18]#[N:19])([CH2:20][n:21]2[n:22][c:23]3[c:24]([n:25][cH:26][c:27]([Br:29])[cH:28]3)[cH:30]2)[CH3:31])[cH:14][cH:15]1Participants
4
Sources & evidence
- ORD record
- ord-e6a054b5e8eb4ecfb6c0d9ce03116048
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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