Tetrahydrofuran → (6-Chloroimidazo[1,2-b]pyridazin-3-yl)(1-methyl-1H-indazol-5-yl)methanol

HRID 800458Notes

Reaction equation

HRID 800458 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[n:7][c:8]([Cl:11])[cH:9][cH:10]2.[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:12][n:13]1[n:14][cH:15][c:16]2[cH:17][c:18]([CH:22]=[O:23])[cH:19][cH:20][c:21]12>>[c:2]1([CH:22]([c:18]2[cH:17][c:16]3[cH:15][n:14][n:13]([CH3:12])[c:21]3[cH:20][cH:19]2)[OH:23])[cH:3][n:4][c:5]2[n:6]1[n:7][c:8]([Cl:11])[cH:9][cH:10]2

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 128723233-Bromo-6-chloroimidazo(1,2-b)pyridazineHCID 378185941-Methyl-1H-indazole-5-carboxaldehyde

Product 1

HCID 58190458(6-Chloroimidazo[1,2-b]pyridazin-3-yl)(1-methyl-1H-indazol-5-yl)methanol

Sources & evidence

ORD record
ord-443dd1ea882d40f9aa436fa8f35a737a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…