Methanol → [2-Bromo-6-(trifluoromethoxy)phenyl]methanol

HRID 800741Notes

Reaction equation

HRID 800741 reaction equation

[BH3:21].[Br:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[c:7]([O:11][C:12]([F:13])([F:14])[F:15])[cH:8][cH:9][cH:10]1.[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1.[CH3:22][OH:23].[O:16]1[CH2:17][CH2:18][CH2:19][CH2:20]1>>[Br:1][c:2]1[c:3]([CH2:4][OH:5])[c:7]([O:11][C:12]([F:13])([F:14])[F:15])[cH:8][cH:9][cH:10]1

Participants

5

Reactant 4

HCID 887Methanol

HCID 6331Borane

HCID 8028Tetrahydrofuran2×

HCID 111088792-Bromo-6-(trifluoromethoxy)benzoic acid

Product 1

HCID 66770602[2-Bromo-6-(trifluoromethoxy)phenyl]methanol

Sources & evidence

ORD record: ord-bc6cac3555704035ab8101e7aecb795e
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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