Water → tert-Butyl 6-chloro-1,2,3,4-tetrahydroquinolin-3-ylcarbamate

HRID 801040Notes

Reaction equation

HRID 801040 reaction equation
[CH3:28][C:29]#[N:30].[Cl:19][N:20]1[C:21](=[O:22])[CH2:23][CH2:24][C:25]1=[O:26].[NH:1]1[CH2:2][CH:3]([NH:11][C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[OH2:27]>>[NH:1]1[CH2:2][CH:3]([NH:11][C:12]([O:13][C:14]([CH3:15])([CH3:16])[CH3:17])=[O:18])[CH2:4][c:5]2[cH:6][c:7]([Cl:19])[cH:8][cH:9][c:10]21

Participants

5

Reactant 4

HCID 962WaterHCID 6342AcetonitrileHCID 31398ChlorosuccinimideHCID 4460996Boc-3-amino-1,2,3,4-tetrahydroquinoline

Product 1

HCID 59297067tert-Butyl 6-chloro-1,2,3,4-tetrahydroquinolin-3-ylcarbamate

Sources & evidence

ORD record
ord-e0a33fdecad549248b1be5507b18a045
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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