Hydrochloric Acid → 4-(6-Methoxy-7-morpholin-4-yl-quinazolin-4-yl)-piperidine-1-carboxylic acid (4-morpholin-4-yl-phenyl)-amide
Reaction equation
[C:1]([CH3:3])([CH3:4])([O:5][C:6](=[O:2])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([N:26]4[CH2:27][CH2:28][O:29][CH2:30][CH2:31]4)[c:21]([O:24][CH3:25])[cH:22][c:23]23)[CH2:12][CH2:13]1)[CH3:7].[ClH:32].[N+:33]([c:34]1[cH:35][cH:36][c:37]([O:38][C:39](=[O:40])[NH:44][c:45]2[cH:46][cH:47][c:48]([N:51]3[CH2:52][CH2:53][O:54][CH2:55][CH2:56]3)[cH:49][cH:50]2)[cH:41][cH:42]1)([O-:43])=[O:57]>>[O:5]=[C:6]([N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([N:26]4[CH2:27][CH2:28][O:29][CH2:30][CH2:31]4)[c:21]([O:24][CH3:25])[cH:22][c:23]23)[CH2:12][CH2:13]1)[NH:44][c:45]1[cH:46][cH:47][c:48]([N:51]2[CH2:52][CH2:53][O:54][CH2:55][CH2:56]2)[cH:49][cH:50]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-4d52625ab68d4ea89f215dc826ede0e6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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